About the job
Job Title: Scientist II- Cell Engineering
Location: New York City, USA
Compensation Range: $100,000-$120,000
Join Us in Revolutionizing Women’s Ovarian Health
We are seeking an experienced, highly motivated Scientist II to join our innovative team at Gameto. This is a unique opportunity to lead cutting-edge research at the intersection of cell biology, biotechnology, and women’s health, contributing directly to the development of novel cell therapies for menopause. Our mission is to transform the future of endocrine care for women by advancing therapeutic solutions that make a meaningful impact.
If you are passionate about scientific discovery, thrive in dynamic environments, and possess advanced expertise in pluripotent stem cell culture and differentiation, this role offers a platform for you to drive innovation in translational research.
About the Role
Gameto is pioneering next-generation cell therapies for reproductive health. We are seeking a highly motivated and technically skilled Cell Engineer with deep experience in pluripotent stem cell manipulation, gene editing, and directed differentiation to join our growing research team. The ideal candidate will have a strong PhD foundation and 0–2 years of postdoctoral or industry experience engineering stem cells, including transcription factor-mediated lineage specification, molecular cloning, and molecular analysis.
This is an exciting opportunity to shape the future of cell therapy and regenerative medicine with a talented, mission-driven team.
Key Responsibilities
- Lead and execute experimental plans for engineering and differentiating human iPSCs (hiPSCs) toward reproductive cell fates or other target lineages.
- Design and perform gene editing using transposon-based editing or related systems to engineer reporter lines or modulate gene function.
- Implement transcription factor-mediated differentiation protocols and systematically optimize lineage commitment.
- Apply molecular cloning strategies for construct generation and cell engineering workflows.
- Develop and validate high-throughput functional screening approaches to assess differentiation efficiency and phenotype.
- Analyze and interpret complex multi-modal datasets (e.g., RNA-seq, qPCR, flow cytometry, ELISA, viability assays) to guide iteration.
- Contribute to the development of 3D cell culture, organoid models, or encapsulation systems for in vitro evaluation.
- Collaborate across cell biology, biomaterials, and bioinformatics teams to align strategies with company milestones.
- Prepare and present data at internal reviews, external partnerships, and scientific conferences.
- Maintain accurate, detailed electronic lab notebooks and adhere to rigorous scientific and safety standards.
Required Qualifications
- Ph.D. in Cell Biology, Molecular Biology, Biomedical Engineering, Genetics, or related field.
- 0–2+ years of relevant postdoctoral or industry experience in a cell engineering or stem cell lab.
- Proven expertise with hiPSC maintenance, genetic modification, and differentiation protocols.
- Strong molecular biology toolkit, including CRISPR/Cas9/Transposon/Lentivirus editing, cloning, and construct design.
- Experience with transcription factor-based programming or directed lineage specification.
- Hands-on proficiency in functional assays, ELISA, RNA-seq, and single-cell analysis techniques.
- Strong familiarity with 3D cell culture, organoids, microfluidics, or encapsulation systems is a plus.
- Excellent problem-solving skills and ability to work independently while contributing to collaborative goals.
- Strong communication and data presentation skills.
- Detail-oriented and organized, with a commitment to high-quality lab practice.
How to Apply
If you are excited about advancing women’s health through cutting-edge science and want to be part of a mission-driven team, we encourage you to apply today!
Please apply on LinkedIn and with the following materials together in a single PDF document:
- A cover letter that:
- Highlights your experience in bioinformatics and relevance to this role
- Shares your interest in Gameto and anticipated start date
- Provides any other information you’d like us to consider
- CV/resume
Why Join Us?
At Gameto, you’ll have the chance to work alongside top scientists and engineers at the intersection of cell biology, computational science, and women’s health. As a Bioinformatics Scientist, your insights will shape the development, quality, and impact of novel therapies. Your work will contribute directly to advancing women’s health through innovation and precision.
About Gameto
Gameto is a pioneering biotechnology company in women’s health, co-founded by Dina Radenkovic, a physician-turned-entrepreneur, and Martin Varsavsky, a leader in fertility innovation and founder of the Prelude Network.
With our groundbreaking cell engineering platform—developed through a collaboration with Harvard University’s Wyss Institute and Professor George Church’s lab at Harvard Medical School—we aim to create treatments for menopause and infertility affecting the female reproductive system. Our scientific approach surpasses traditional therapeutic modalities and sets a new gold standard for research and development in the field.
Backed by $73 million raised in Series A and B funding from Insight Partners, Future Ventures, RA Capital, Two Sigma Ventures, Lux Capital, and others as well as $10 million from ARPA-H, Gameto is committed to transforming women’s healthcare through bold innovation.
Read about us in: MIT Technology Review, The New Yorker, The Boston Globe, and Stat News.
Our Values and Commitment to Diversity
At Gameto, we value kindness, collaboration, authenticity, and diversity. We are an equal opportunity employer and are committed to creating an inclusive environment. We do not discriminate based on race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.