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Study demonstrates the generation of ovarian support cells (OSCs) from hiPSCs through the induced expression of specific transcription factors

Study conducted in partnership with the George Church Lab at The Wyss Institute of Harvard Medical School describes a novel protocol to generate granulosa-like cells through targeted transcription factor overexpression.

Findings

Clinical Significance

This model system will provide unique opportunities for studying human ovarian biology and may enable the development of therapies for female reproductive health.

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